I’ll start with a hardcore science explanation and then second I’ll explain what this means for the practical use of phenibut.
Phenibut was an acid artifically created in Russia and released as a dieting supplement. It binds to GABA B receptors in the brain, similar to GHB, a euphoric street drug and sedative, though it’s illegal. Phenibut is perfectly legal and differs from GABA A drugs such as alcohol. This slight chemical difference in the receptors phenibut “agonizes” or hits are why phenibut is not a more severe drug. Phenibut falls under the blanket term nootropic, meaning it’s a “smart drug” that enhances your brain. It comes in the form of a semi-fine powder, with granules about half as small as typical table salt. It is best taken on an empty stomach or else it may take longer to kick in and lose effectiveness.
One of the most notable things about phenibut it is very slow-acting. Though minor effects can be felt in the first few hours of taking, it typically takes 5-8 hours to feel the full extent of phenibut. Sometimes this comes as a “peak” or “wave” that can last up to hours, but then taper off, leading either to an eventual relaxing “down” or in some cases a crash. Crashes with phenibut aren’t common, however, unlike stimulants like caffeine. A “hangover” with phenibut usually is positive unless coming directly out of sleep while one is still tired.
Because of the slow-acting nature of phenibut, it can’t be used on-demand if taken orally. You have to take it hours beforehand. Experimenting with the drug will tell you what the best way for you to take it is depending on your metabolism. Some may experience a slow-burn, others might feel effects in just 5 hours, others might take longer. Refer to the Phenibut God Dosing Method for a guide on how to use the drug.
Taste-wise, phenibut is very bitter and has an almost sweet aftertaste than can linger on the lips or tongue, like toothpaste. Swishing with a bit of water can easily remove this taste. It’s best not to take phenibut actually dissolved in water, but rather salivate your mouth beforehand and drop phenibut in the middle of the tongue, and then swallow. The goal is not to savor it in your mouth but also not to let it hit the back of your throat and “burn” it.
Once the phenibut is in your system, nothing immediate will happen. You may feel placebo effects, but generally in 2-3 hours you will start to feel minor side effects. After a full 5-7 hours you should be feeling much different, and for some there will be a “peak” where phenibut suddenly “kicks in.” Enjoy this period for a while and eventually the drug will taper down and work in the background. This “passive” burn can last 24 hours or more, meaning you can be feeling the effects the next day. This is why, to avoid addiction, it’s best to cycle phenibut and either not take it every day or have periods off. Too much GABA in the brain can make you tolerant of the drug, and dependent on it. But Phenibut still has a minor withdrawal and overall its positive effects outweigh the negative.